Castle Biosciences (NASDAQ:CSTL) is set to give its latest quarterly earnings report on Thursday, 2026-02-26. Here’s what investors need to know before the announcement.
Analysts estimate that Castle Biosciences will report an earnings per share (EPS) of $-0.24.
Castle Biosciences bulls will hope to hear the company announce they’ve not only beaten that estimate, but also to provide positive guidance, or forecasted growth, for the next quarter.
New investors should note that it is sometimes not an earnings beat or miss that most affects the price of a stock, but the guidance (or forecast).
Overview of Past Earnings
The company’s EPS beat by $0.42 in the last quarter, leading to a 21.7% increase in the share price on the following day.
Here’s a look at Castle Biosciences’s past performance and the resulting price change:
| Quarter | Q3 2025 | Q2 2025 | Q1 2025 | Q4 2024 |
|---|---|---|---|---|
| EPS Estimate | -0.44 | -0.50 | -0.07 | 0.04 |
| EPS Actual | -0.02 | 0.15 | -0.20 | 0.32 |
| Price Change % | 21.70 | 32.83 | -11.36 | -14.24 |
Stock Performance
Shares of Castle Biosciences were trading at $29.94 as of February 24. Over the last 52-week period, shares are up 20.98%. Given that these returns are generally positive, long-term …