Burlingame, CA, Aug. 08, 2025 (GLOBE NEWSWIRE) — The global Baculovirus Expression System Market is estimated to be valued at USD 436.0 Mn in 2025 and is expected to reach USD 781.8 Mn in 2032, exhibiting a compound annual growth rate (CAGR) of 8.7% from 2025 to 2032. The baculovirus expression system market is expanding steadily, driven by its growing use in producing recombinant proteins, vaccines, and gene therapy vectors due to its high expression efficiency and scalability. Rising demand for advanced biologics, increasing investment in vaccine development, and the surge in research for novel therapeutics are fueling market growth. Technological advancements, such as improved vector design and enhanced expression yields, are creating new opportunities for biopharmaceutical manufacturing. With expanding applications in cancer research, infectious disease treatment, and personalized medicine, the baculovirus expression system market offers significant demand opportunities in both research and commercial bioproduction sectors.
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Global Baculovirus Expression System Market Key Takeaways
According to Coherent Market Insights (CMI), the global baculovirus expression system market size is expected to reach USD 781.8 Mn by 2032, up from USD 436 Mn in 2025, registering a CAGR of 8.7%.
Therapeutics remain the most lucrative application for baculovirus expression systems, accounting for 38% of the global market share in 2025.
North America is set to dominate the industry, accounting for more than one-third of the global baculovirus expression system market share in 2025.
Europe, with an estimated share of over one-fourth in 2025, is expected to remain the second-largest market for baculovirus expression system companies.
Asia Pacific market is poised to record the fastest growth during the assessment period.
Soaring Demand for Recombinant Proteins Propelling Market Growth
Coherent Market Insights’ latest baculovirus expression system market research report lists major factors driving industry growth. Increasing demand for recombinant proteins is one such growth driver.
Recombinant proteins are witnessing high demand due to their broad application in therapeutic development, vaccine production, and biomedical research. They are becoming essential in drug discovery and disease treatment due to their ability to mimic natural proteins with high precision.
Baculovirus expression systems (BES) are especially valued for their efficiency in producing complex recombinant proteins, especially eukaryotic proteins. As the demand for these sophisticated proteins rises, the need for advanced expression systems like baculovirus is expected to grow correspondingly, driving market growth.
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High Production Costs and Adoption of Alternatives Hampering Market Growth
The prospective baculovirus expression system market outlook looks promising, owing to rising demand for recombinant proteins. However, high production costs and competition for alternative expression systems present a significant barrier to widespread market expansion.
Baculovirus expression system involves complex production processes and specialized infrastructure, leading to high operational costs. These factors limit its adoption and dampen overall baculovirus expression system market demand.
Moreover, many pharmaceutical and biopharmaceutical companies opt for alternative expression systems like CHO cells, yeast, and E. coli as they are more established and cost-effective. This trend may further hinder …